Hiroshi Iwasaki

Fission yeast Swi2 designates cell-type specific donor and stimulates Rad51-driven strand exchange

The paper identifies two motifs in the Swi2-Swi5 complex that enable cell-type-specific localization to recombination enhancers and stimulate Rad51-driven gene conversion in fission yeast.

Euchromatin factors HULC and Set1C affect heterochromatin organization for mating-type switching in fission yeast Schizosaccharomyces pombe

This study identifies HULC and Set1C as factors that regulate heterochromatin organization during mating-type switching in fission yeast by controlling recombination enhancer usage and histone modifications.

Rrp1 translocase and ubiquitin ligase activities restrict the genome destabilising effects of Rad51 in fission yeast

This study shows Rrp1 counteracts Rad51 activity in fission yeast through ATPase and ubiquitin ligase functions, preventing genome instability.

Real-time tracking reveals the catalytic process of Rad51-driven DNA strand exchange

This study reveals the roles of Rad51's DNA binding motifs in the catalytic process of DNA strand exchange during homologous recombination.

Rad51 Interaction Analysis Reveals a Functional Interplay Among Recombination Auxiliary Factors

The paper identifies two binding sites on Sfr1 that interact with Rad51 and shows that Swi5-Sfr1 requires Rad55-Rad57 for DNA repair.