Bilge Argunhan

Structures and molecular mechanisms of RAD54B in modulating homologous recombination

This paper defines the role of RAD54B in homologous recombination using cryo-EM and biochemical assays, showing it stabilizes RAD51 filaments and promotes D-loop formation.

RAD51AP1 is a versatile RAD51 modulator

This paper identifies RAD51AP1 as a versatile modulator of RAD51, revealing its role in stabilizing RAD51-ssDNA filaments and promoting strand exchange through multiple binding sites.

Rrp1 translocase and ubiquitin ligase activities restrict the genome destabilising effects of Rad51 in fission yeast

This study shows Rrp1 counteracts Rad51 activity in fission yeast through ATPase and ubiquitin ligase functions, preventing genome instability.

Real-time tracking reveals the catalytic process of Rad51-driven DNA strand exchange

This study reveals the roles of Rad51's DNA binding motifs in the catalytic process of DNA strand exchange during homologous recombination.

Rad51 Interaction Analysis Reveals a Functional Interplay Among Recombination Auxiliary Factors

The paper identifies two binding sites on Sfr1 that interact with Rad51 and shows that Swi5-Sfr1 requires Rad55-Rad57 for DNA repair.