A SARS-CoV-2 targeted siRNA-nanoparticle therapy for COVID-19
Adi Idris, Alicia M. Davis, Aroon Supramaniam, Dhruba Acharya, Gabrielle Kelly, Yaman Tayyar, Nicholas P. West, Ping Zhang, Christopher L. D. McMillan, Citradewi Soemardy, Roslyn Michelle Ray, Denis O’Meally, Tristan A. Scott, Nigel A.J. McMillan, Kevin V. Morris
This paper develops an siRNA-nanoparticle therapy targeting SARS-CoV-2 that reduces viral load and improves survival in mice.
Molecular Therapy · May 13, 2021Peer-reviewedSynthetic Biology