Author
The University of QueenslandORCID 0000-0002-5316-0986Unclaimed ORCID profile · follow to get notified of new preprints
7 papers
Recent·Most cited
Laura Jane Leighton, Yee Jing Gee, Sachithrani U. Madugalle…·Seth W. Cheetham
This study shows that mRNA-LNPs can efficiently deliver mRNA to hepatocytes in healthy and diseased livers, including tumors, suggesting potential for systemic mRNA therapy in liver cancer.
Rhys H. Parry, Christopher L. D. McMillan, Kimberley L. Bruce, Helen E. Farrell
This study identifies how cytomegalovirus infection reprograms murine dendritic cells to suppress MHC class II antigen presentation while enhancing migration machinery, with M33 specifically boosting migration-related genes.
Rhys H. Parry, Yingjun Shang, Julian D. J. Sng…·Alexander A. Khromykh
The paper evaluates vaccine-induced and hybrid immunity against SARS-CoV-2 variants in two cohorts, finding reduced antibody titres and neutralization activity against Omicron variants, with some recovery after multiple vaccinations.
P. Prakrithi, Laura F. Grice, Feng Zhang…·Quan Hoang Nguyen
The paper integrates 12 spatial and single-cell technologies to analyze cellular interactions and signatures in three skin cancers, identifying key therapeutic targets and genetic associations.
Ariel Isaacs, Guillermo Valenzuela, Xinghai Zhang…·Daniel Watterson
This paper develops a bispecific antibody that targets both Nipah virus surface glycoproteins, reducing viral escape and enhancing protection against NiV disease.
Eduardo A. Albornoz, Alberto Anastacio Amarilla, Naphak Modhiran…·Trent M. Woodruff
This study shows SARS-CoV-2 activates microglial NLRP3 inflammasome via spike-ACE2 interaction, potentially linking viral infection to neurological symptoms like Parkinson's.
Adi Idris, Alicia M. Davis, Aroon Supramaniam…·Kevin V. Morris
This paper develops an siRNA-nanoparticle therapy targeting SARS-CoV-2 that reduces viral load and improves survival in mice.