Author

Jacqueline Nakel

Leibniz Institute of Virology (LIV)ORCID 0000-0002-0161-5571Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:statistical model· 2 Research Focus:differential expression· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1 Research Focus:trajectory inference· 1

Frequent Co-Authors

Adam T. GrundhoffiD· 2 shared Thomas GüntheriD· 2 shared Bente SiebelsiD· 1 shared Birgit Schwanke· 1 shared Carola Schneider· 1 shared Caroline C. FriedeliD· 1 shared Claudia S. SchmidtiD· 1 shared Daniela IndenbirkeniD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersNeuroscience

Adam T. GrundhoffORCID

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2 papers

Recent·Most cited

Temporal Profiling of Upper-Layer Neurons Reveals Changes in the Molecular Landscape Upon Maternal Immune Activation

Tabitha Rücker, Birgit Schwanke, Kerstin Reumann, Patrick Blümke, Jacqueline Nakel, Daniela Indenbirken, Thomas Günther, Thomas Mair, Bente Siebels, Paula Nissen, Kilian Müller, Melanie Richter, Sabine Hoffmeister‐Ullerich, Stephanie Stanelle‐Bertram, Gülşah Gabriel, , Froylán Calderón de Anda

This study maps the molecular changes in murine upper-layer cortical neurons during development and shows how maternal immune activation disrupts this process through post-transcriptional and signaling mechanisms.

bioRxiv · Apr 16, 2026 · PreprintNeuroscience

Merkel cell polyomavirus small tumor antigen contributes to immune evasion by interfering with type I interferon signaling

Denise Ohnezeit, Jiabin Huang, Ute Westerkamp, Veronika Brinschwitz, Claudia S. Schmidt, Thomas Günther, Manja Czech‐Sioli, Samira Weißelberg, Tabea Schlemeyer, Jacqueline Nakel, Julia Mai, Sabrina Schreiner, Carola Schneider, Caroline C. Friedel, Hella Schwanke, , Nicole Fischer

This study identifies a novel function of MCPyV small T antigen in suppressing the type I interferon response by reducing IRF9 levels, impacting immune evasion and tumor progression.

PLoS Pathogens · Aug 7, 2024Peer-reviewedMolecular Biology