Author

Sheerazed Boulkroun

InsermORCID 0000-0002-8796-7534Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:clustering· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Bakhta FedlaouiiD· 2 shared Fabio Luiz Fernandes-RosaiD· 2 shared Isabelle Giscos-Douriez· 2 shared Maria‐Christina ZennaroiD· 2 shared May FayadiD· 2 shared Nicolò FaeddaiD· 2 shared Stéphanie BaroniD· 2 shared Alaa B Abdellatif· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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2 shared papersPhysiology

Bakhta FedlaouiORCID

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2 papers

Recent·Most cited

Sexually dimorphic interzonal crosstalk reshapes the adrenal cortex in response to pathophysiological challenges

Nicolò Faedda, Alaa B Abdellatif, Francesco Carbone, May Fayad, Bakhta Fedlaoui, Rita Chamoun, Romane L’Héritier, Ilaria Del Gaudio, Ourida Koual, Isabelle Giscos-Douriez, Stéphanie Baron, Ben Atkinson, Xiaomin Li, Linghui Kong, Yunling Xu, , Maria‐Christina Zennaro

This study shows that environmental factors like diet and dexamethasone induce sex-specific changes in adrenal cortex zones through cell lineage conversion and transcriptional reprogramming.

bioRxiv · Sep 5, 2025 · PreprintPhysiology

Modulation of calcium signaling on demand to decipher the molecular mechanisms of primary aldosteronism

Bakhta Fedlaoui, Teresa Cosentino, Zeina Reda Al Sayed, Rita Alexandre Coelho, Isabelle Giscos-Douriez, Nicolò Faedda, May Fayad, Jean‐Sébastien Hulot, Christopher J. Magnus, Scott M. Sternson, Simon Travers-Allard, Stéphanie Baron, David Pentón, Fabio Luiz Fernandes-Rosa, Maria‐Christina Zennaro, Sheerazed Boulkroun

This study establishes an adrenocortical cell model to modulate sodium entry and calcium signaling, revealing its role in aldosterone biosynthesis and PA development.

Hypertension · Feb 12, 2025Peer-reviewedPhysiology