Author

Jean C. Manson

University of EdinburghORCID 0000-0002-0175-9890Unclaimed ORCID profile · follow to get notified of new preprints

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Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Alan Richard ClarkeiD· 1 shared Alison Marshall· 1 shared Barry Matthew BradfordiD· 1 shared Deborah Brown· 1 shared Dorothy KisielewskiiD· 1 shared KIM M. SUMMERSiD· 1 shared Nadia L. Tuzi· 1 shared Pedro Piccardo· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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1 shared paperNeuroscience

Alan Richard ClarkeORCID

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1 paper

Recent·Most cited

Therapeutic window for treatment of prion disease defined by timed depletion of Prion protein

Barry Matthew Bradford, Alison Marshall, Nadia L. Tuzi, Deborah Brown, Dorothy Kisielewski, KIM M. SUMMERS, Victor Hugh Perry, Pedro Piccardo, Alan Richard Clarke, Jean C. Manson

This study defines a therapeutic window for prion disease by showing early Prnp depletion halts progression, but later depletion does not, using a mouse model with time-dependent Prnp manipulation.

bioRxiv · Nov 18, 2024 · PreprintNeuroscience