Author

Elizabeth M. Guettler

Lady Davis Institute for Medical ResearchORCID 0000-0002-0176-9407Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Andrew MitchelliD· 1 shared Christophe GonçalvesiD· 1 shared Daniel González‐MorenoiD· 1 shared Feiyang CaiiD· 1 shared José Ferro· 1 shared Kelly CoutantiD· 1 shared Natascha GagnoniD· 1 shared Noah Wirasinghe· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Andrew MitchellORCID

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1 paper

Recent·Most cited

RAB1A is a novel vulnerability in uveal melanoma revealed by dual inhibition of MNK1/2 and mTOR.

Raúl Ernesto Flores González, Christophe Gonçalves, Noah Wirasinghe, Véronique Gaudreault, José Ferro, Kelly Coutant, Andrew Mitchell, Theodore Papadopoulos, Y. G. Cho, Elizabeth M. Guettler, Daniel González‐Moreno, Samuel E.J. Preston, Feiyang Cai, Natascha Gagnon, Steve Jean, , Sonia Victoria Del Rincon

This study identifies RAB1A as a vulnerability in uveal melanoma through dual inhibition of MNK1/2 and mTOR, showing it disrupts protein trafficking and blocks liver metastasis.

Cell Death and Differentiation · Feb 18, 2026Peer-reviewedCancer Biology