Munichandra Babu Tirumalasetty

GLP1R Variants and Polygenic Risk Underlie Heterogeneous Response to GLP-1 Receptor Agonists in Type 2 Diabetes

This study identifies genetic and clinical factors influencing glycemic response to GLP-1 receptor agonists in type 2 diabetes, showing that polygenic risk and GLP1R variants are associated with response variability.

NgBR controls hepatic adiponectin signaling competence through KAT7-dependent chromatin regulation

This study identifies NgBR as a regulator of hepatic adiponectin sensitivity, showing that it maintains adiponectin receptor competence through KAT7-dependent chromatin regulation.

Extracellular vesicles from chylomicron-treated endothelial cells drive macrophage inflammation

This study shows that chylomicron-treated endothelial cells release extracellular vesicles that drive macrophage inflammation and lipid droplet formation.

FerroEnrich: An Interactive web tool for computing Ferroptosis index and gene enrichment.

FerroEnrich computes ferroptosis index and gene enrichment using gene expression data through an interactive web tool.