Richa Banerjee

Lymphatic Malformations with Activating KRAS Mutations Impair Lymphatic Valve Development Through Matrix Metalloproteinases

This study shows that KRAS mutations impair lymphatic valve development by upregulating MMPs, which degrade the valve ECM core.

Rictor induces AKT signaling to regulate lymphatic valve formation

This study shows that Rictor is essential for AKT signaling in lymphatic valve formation, as its deletion reduces valve numbers and impairs valve maturation.

Endothelial Nitric Oxide Synthase Regulates Lymphatic Valve Specification By Controlling β-catenin Signaling During Embryogenesis

This study shows eNOS regulates lymphatic valve specification by controlling β-catenin signaling during embryogenesis, independent of nitric oxide production.