George E. Davis

This study shows that KRAS mutations impair lymphatic valve development by upregulating MMPs, which degrade the valve ECM core.

This study identifies TNF and endothelial IL-1R1 signaling as key drivers of capillary regression and fibrosis in obstructive kidney injury, showing that their combined inhibition preserves peritubular capillaries and reduces renal injury.

This paper shows that Lats1/2 are essential for vascular remodeling and response to shear stress in embryonic endothelial cells, leading to vascular defects and embryonic lethality.

This study shows that SHE and ABL signaling regulate vascular lumen size in zebrafish and human endothelial cells by modulating claudin expression and cell proliferation.