Author

Onofrio Laselva

University of FoggiaORCID 0000-0002-0237-4079Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 1 Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:statistical model· 1 Research Focus:trajectory inference· 1

Frequent Co-Authors

Christine E. BeariD· 3 shared Sunny XiaiD· 3 shared Amy P. WongiD· 2 shared Jia Xin Jiang· 2 shared Michelle Di PaolaiD· 2 shared Zoltán BozókyiD· 2 shared Amy L. Pitstick· 1 shared Chong JiangiD· 1 shared

Activity by Year

2021-2021 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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3 shared papersMolecular Biology

Christine E. BearORCID

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Author profile →

3 papers

Recent·Most cited

High-throughput functional analysis of CFTR and other apically localized channels in iPSC derived intestinal organoids

Sunny Xia, Zoltán Bozóky, Onofrio Laselva, Michelle Di Paola, Saumel Ahmadi, Jia Xin Jiang, Amy L. Pitstick, Chong Jiang, Daniela Rotin, Christopher N. Mayhew, Nicola L. Jones, Christine E. Bear

The paper describes a high-throughput fluorescence-based assay to measure CFTR and other apical membrane protein activity in iPSC-derived intestinal organoids.

Cells · Dec 4, 2021Peer-reviewedMolecular Biology

A new platform for high-throughput therapy testing on iPSC-derived, immature airway from Cystic Fibrosis Patients

Jia Xin Jiang, Leigh Wellhauser, Onofrio Laselva, Irina Utkina, Zoltán Bozóky, Tarini Nawamalie Abeysinghe Gunawardena, Zoe Ngan, Sunny Xia, Michelle Di Paola, Paul D. W. Eckford, Felix A. Ratjen, Theo J. Moraes, John Parkinson, Amy P. Wong, Christine E. Bear

This paper describes a fluorescence-based platform for high-throughput Cystic Fibrosis therapy testing using iPSC-derived immature airway epithelium.

Stem Cell Reports · Oct 22, 2021Peer-reviewedGenomics

Modeling lung cell development using human pluripotent stem cells

Shuk Yee Ngan, Henry T. Quach, Joshua G. Dierolf, Onofrio Laselva, Jin A Lee, Elena N. Huang, Maria Mangos, Sunny Xia, Christine E. Bear, Amy P. Wong

This study uses human pluripotent stem cells to model lung development, generating renewable lung epithelial spheroids and identifying new cell lineage relationships.

bioRxiv · Jul 16, 2021 · PreprintDevelopmental Biology