Author

Maria Mangos

University of Toronto

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Developmental Biology· 1 Microbiology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Liliana AttisanoiD· 3 shared Adam Sivitilli· 1 shared Aizhou WangiD· 1 shared Alan CochraneiD· 1 shared Alencar Kolinski MachadoiD· 1 shared Ali Zahedi AmiriiD· 1 shared Amin YarmandiD· 1 shared Amy P. WongiD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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3 shared papersBioengineering

Liliana AttisanoORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Physiological perfusion of human vasculature reveals a YAP/TAZ-Apelin switch linking intraluminal flow to endothelial state transitions and vessel remodeling

Jian, Tiger, H, Z, Adam Sivitilli, Yaxin E. Guo, Callum Stirton, Jessica Gosio, Yuko Tsukahara, Johnny M. Tkach, Suying Lu, Amin Yarmand, Maria Mangos, Rod Bremner, Jeffrey L. Wrana, Liliana Attisano, Laurence Pelletier

The paper introduces VIVOS, a 3D human vascular platform that links intraluminal flow to endothelial state transitions and vessel remodeling through YAP/TAZ-Apelin signaling.

bioRxiv · Mar 24, 2026 · PreprintBioengineering

Bioactive Flavonoid Extract Suppresses NLRP3 Activation and Inflammation in 2D and 3D Lung Models

Dana El Soufi El Sabbagh, Diulie Valente de Souza, Lauren Pappis, Carolina Bordin Davidson, Maria Mangos, Aizhou Wang, Marcelo Cypel, Liliana Attisano, Alencar Kolinski Machado, Ana C. Andreazza

This study examines how a bioactive flavonoid extract suppresses NLRP3 inflammasome activation and inflammation in both 2D and 3D lung models.

bioRxiv · Feb 20, 2025 · PreprintMolecular Biology

Exploiting the Achilles' Heel of Viral RNA Processing to Develop Novel Antivirals

Ali Zahedi Amiri, Choudhary Ahmed, Subha Dahal, Filomena Grosso, Haomin Leng, Peter Stoilov, Maria Mangos, Johanne Toutant, Lulzim Shkreta, Liliana Attisano, Benoı̂t Chabot, Martha Brown, Mario Huesca, Alan Cochrane

This paper identifies 5342191 as a broad-spectrum antiviral that inhibits HIV-1, adenovirus, coronavirus, and influenza by altering viral RNA accumulation and structural protein expression.

Viruses · Dec 31, 2024Peer-reviewedMicrobiology

Modeling lung cell development using human pluripotent stem cells

Shuk Yee Ngan, Henry T. Quach, Joshua G. Dierolf, Onofrio Laselva, Jin A Lee, Elena N. Huang, Maria Mangos, Sunny Xia, Christine E. Bear, Amy P. Wong

This study uses human pluripotent stem cells to model lung development, generating renewable lung epithelial spheroids and identifying new cell lineage relationships.

bioRxiv · Jul 16, 2021 · PreprintDevelopmental Biology