Sunny Xia

Benchmarking organ-specific responses to therapies in tissues differentiated from Cystic Fibrosis patient derived iPSCs

This study benchmarks Trikafta's efficacy in CF patient-derived iPSC-derived colonic and airway tissues compared to isogenic controls, showing differential therapeutic responses.

High-throughput functional analysis of CFTR and other apically localized channels in iPSC derived intestinal organoids

The paper describes a high-throughput fluorescence-based assay to measure CFTR and other apical membrane protein activity in iPSC-derived intestinal organoids.

A new platform for high-throughput therapy testing on iPSC-derived, immature airway from Cystic Fibrosis Patients

This paper describes a fluorescence-based platform for high-throughput Cystic Fibrosis therapy testing using iPSC-derived immature airway epithelium.

Modeling lung cell development using human pluripotent stem cells

This study uses human pluripotent stem cells to model lung development, generating renewable lung epithelial spheroids and identifying new cell lineage relationships.