Author

David Parker

Emory UniversityORCID 0000-0002-0240-4741Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2 Approach:benchmark study· 1 Assay:bulk RNA-seq· 1 Research Focus:gene regulatory network inference· 1 Assay:GWAS summary statistics· 1

Frequent Co-Authors

Bradley D. PearceiD· 1 shared Brett A. ClementziD· 1 shared Carol A. TammingaiD· 1 shared Carrie E. BeardeniD· 1 shared Chao CheniD· 1 shared Christina MichalskiiD· 1 shared Chunyu LiuiD· 1 shared Cindy H. WeniD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperNeuroscience

Bradley D. PearceORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Synaptic microRNA dysregulation orchestrates aberrant glutamatergic transmission in a human neuronal model of 22q11.2 deletion syndrome

Weibo Niu, Jidong Guo, Ximing Ran, David Parker, Xiangru Li, Shaojun Yu, Sidney Imes, Ryan H. Purcell, Christina Michalski, Eric Guo, Sophia Y Jiang, Ethan Xu, Gary Jonathan Bassell, Jennifer Gladys Mulle, Opal Ousley, , Zhexing Wen

This study identifies dysregulated synaptic microRNAs in 22q11DS neurons that drive aberrant glutamatergic transmission and synaptic plasticity, linking genetic deletion to psychosis risk.

bioRxiv · Oct 15, 2026 · PreprintNeuroscience

Genetic Analysis of Psychosis Biotypes: Shared Ancestry-Adjusted Polygenic Risk and Unique Genomic Associations

Cuihua Xia, Ney Alliey‐Rodriguez, Carol A. Tamminga, Matcheri S. Keshavan, Godfrey D. Pearlson, Sarah Keedy, Brett A. Clementz, Jennifer E. McDowell, David Parker, Rebekka Lencer, S. Kristian Hill, Jeffrey R. Bishop, Elena I. Ivleva, Cindy H. Wen, Rujia Dai, , Elliot S. Gershon

The paper analyzes psychosis biotypes using ancestry-adjusted polygenic risk scores and identifies genomic associations with specific biotypes in brain transcriptomes.

Molecular Psychiatry · Dec 21, 2024Peer-reviewedGenetic & Genomic Medicine