Adaptive Replication Fork Acceleration by CDK1-Cyclin B1 Sustains Genome Duplication despite Impaired Origin Firing
Md Shahadat Hossain, Courtney G. Sansam, Krishanu Dhar, Christopher L. Sansam
The paper shows that cells compensate for reduced replication origin firing by accelerating replication fork progression through a CDK1-RIF1 mechanism.