Author

Diane K. O’Dowd

University of California, IrvineORCID 0000-0002-0266-0729Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Neuroscience· 3

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:electronic health records· 3 Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 2 Research Focus:differential expression· 2 Organism:Drosophila· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Yunyao XieiD· 2 shared An T. Pham· 1 shared Antara DasiD· 1 shared Bingyao Zhu· 1 shared Bryon SilvaiD· 1 shared Carmen M. RamosiD· 1 shared Dafni Hadjieconomou· 1 shared David Vo· 1 shared

Activity by Year

2019-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersNeuroscience

Yunyao XieORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

The Innexin 7 gap junction protein contributes to synchronized activity in the Drosophila antennal lobe and regulates olfactory function

Nicolás Fuenzalida‐Uribe, Sergio Hidalgo, Bryon Silva, Saurin M. Gandhi, David Vo, Parham Zamani, Todd C. Holmes, Sercan Sayın, Ilona C Grunwald Kadow, Dafni Hadjieconomou, Diane K. O’Dowd, Jorge M. Campusano

This study shows that Inx7 gap junctions synchronize antennal lobe projection neurons and are essential for olfactory function in Drosophila.

Frontiers in Neural Circuits · Apr 25, 2025Peer-reviewedNeuroscience

Comparisons of dual isogenic human iPSC pairs identify functional alterations directly caused by an epilepsy associated SCN1A mutation

Yunyao Xie, Nathan Norton Ng, Olga Safrina, Carmen M. Ramos, Kevin C. Ess, Philip H. Schwartz, Martin A. Smith, Diane K. O’Dowd

The paper compares dual isogenic human iPSC pairs to identify functional alterations caused by an epilepsy-associated SCN1A mutation and its interaction with genetic background.

Neurobiology of Disease · Nov 28, 2019Peer-reviewedNeuroscience

Interneuron dysfunction in a new knock-in mouse model of SCN1A GEFS+

Antara Das, Bingyao Zhu, Yunyao Xie, Lisha Zeng, An T. Pham, Jonathan C. Neumann, Grant R. MacGregor, Soleil Sun Schutte, Robert F. Hunt, Diane K. O’Dowd

This study introduces a mouse model with a SCN1A mutation linked to GEFS+ and shows that heterozygous mutants develop seizures due to impaired inhibitory interneuron function.

bioRxiv · Nov 21, 2019 · PreprintNeuroscience