Author

Pascale Eede

Humboldt-Universität zu BerlinORCID 0000-0002-0272-8607Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Frank L. HeppneriD· 2 shared Shirin Schneeberger· 2 shared Anastasiya BoltengageniD· 1 shared Andranik IvanoviD· 1 shared Burkhard BecheriD· 1 shared Caroline BraeuningiD· 1 shared Christine KocksiD· 1 shared Dieter BeuleiD· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersNeuroscience

Frank L. HeppnerORCID

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintAug 2, 2021

Diverse but unique astrocytic phenotypes during embryonic stem cell differentiation, culturing and aging

Kiara Freitag, Pascale Eede, Andranik Ivanov…·Frank L. Heppner

The paper compares ESC-derived, neonatal, and adult astrocytes to identify functional and transcriptomic differences across age and culture conditions.

DOI 10.1101/2021.08.02.454573

bulk RNA-seqexperimental assay

𝕏 PostBluesky

NeurosciencebioRxivPreprintApr 25, 2021

The neuroinflammatory interleukin-12 signaling pathway drives Alzheimer's disease-like pathology by perturbing oligodendrocyte survival and neuronal homeostasis

Shirin Schneeberger, Seung Joon Kim, Pascale Eede…·Frank L. Heppner

This study identifies IL-12 as the main driver of neuroinflammation in Alzheimer's disease by affecting oligodendrocyte survival and neuronal homeostasis in a mouse model.

12 citations

mousebulk RNA-seq

𝕏 PostBluesky