Yashuan Chao

Temporal changes in platelet activation and organ dysfunction during invasive Streptococcus pyogenes infection

This study examines temporal changes in platelet activation and organ dysfunction during invasive Streptococcus pyogenes infection in mice, showing platelets contribute to liver dysfunction and may be therapeutic targets.

Design of a Streptolysin O Epitope-Centric Nanoparticle Vaccine Against Streptococcus pyogenes

This paper designs an epitope-centric nanoparticle vaccine against Streptococcus pyogenes using structural mass spectrometry and deep learning to enhance immunogenicity.

A pharmacoproteomic landscape of organotypic intervention responses in gram-negative sepsis

This study uses pharmacoproteomics to analyze treatment responses in a murine sepsis model, identifying distinct response patterns and drug interactions across organs and time.