Author

Clara Simon

Philipps University of MarburgORCID 0000-0002-0298-9858Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Andrea NistiD· 2 shared Bastian StielowiD· 2 shared Ignasi FornéiD· 2 shared Lisa Marie WeberiD· 2 shared Merle Geller· 2 shared Robert LiefkeiD· 2 shared Sabrina Fischer· 2 shared Thorsten StieweiD· 2 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

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2 shared papersMolecular Biology

Andrea NistORCID

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2 papers

Recent·Most cited

Molecular BiologyPLoS BiologyPeer-reviewedAug 13, 2024

SAMD1 suppresses epithelial-mesenchymal transition (EMT) pathways in pancreatic ductal adenocarcinoma

Clara Simon, Inka D. Brunke, Bastian Stielow…·Robert Liefke

This study identifies SAMD1 as a repressor of EMT-related genes in PDAC, showing that its loss increases migration and that FBXO11 ubiquitinates SAMD1 to inhibit its function.

6 citations

humanDNA methylation

𝕏 PostBluesky

Molecular BiologyNucleic Acids ResearchPeer-reviewedMay 14, 2024

IRF2BP2 counteracts the ATF7/JDP2 AP-1 heterodimer to prevent inflammatory overactivation in acute myeloid leukemia (AML) cells

Sabrina Fischer, Lisa Marie Weber, Bastian Stielow…·Robert Liefke

This study shows IRF2BP2 counteracts the ATF7/JDP2 AP-1 heterodimer to prevent excessive inflammation in AML cells, revealing a potential therapeutic target.

10 citations

humanbulk RNA-seq

𝕏 PostBluesky