Molecular BiologyNature BiotechnologyPeer-reviewed
Pythia: Non-random DNA repair allows predictable CRISPR/Cas9 integration and gene editing
Thomas Naert, Taiyo Yamamoto, Shuting Han…·Soeren S. Lienkamp
The paper introduces Pythia, a tool that uses deep learning to predict CRISPR/Cas9 integration and editing outcomes by leveraging non-random DNA repair patterns.