Bhavin S. Khatri

The paper quantifies progressive changes in chromosome shape during cell divisions and finds that an alternative loop capture model explains the observed arm length to width relationship better than the loop extrusion model.

This paper introduces a new mechanism of DNA bending dissipation, bending friction, which explains slow DNA looping dynamics and is independent of ionic conditions.

The paper presents a pipeline to discover and engineer gene drives that overcome resistance in malaria mosquitoes, showing that new resistant alleles can emerge and designing drives that target multiple sites to suppress populations.