Author

Marissa M. Michael

Weill Cornell MedicineORCID 0000-0002-0313-3947Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:clustering· 2 Research Focus:differential expression· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Arshdeep SinghiD· 2 shared Geoffrey J. MarkowitziD· 2 shared Jonathan Villena‐VargasiD· 2 shared Liron YoffeiD· 2 shared Meixian Stephanie Tang· 2 shared Nasser Khaled AltorkiiD· 2 shared Olivier ElementoiD· 2 shared Rachel HonigsbergiD· 2 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersImmunology

Arshdeep SinghORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintAug 12, 2025

Tumor-draining lymph node derived CD8 T cells sustain durable systemic immunity after neoadjuvant IL-15 and PD-1 blockade

Tatiana Cruz, Rachel Honigsberg, Geoffrey J. Markowitz…·Jonathan Villena‐Vargas

Neoadjuvant IL-15 with PD-1 blockade expands lymph node clonal diversity and preserves stem-like CD8 T cell features, yielding superior antitumor efficacy, durable memory, and reduced metastatic recurrence.

DOI 10.1101/2025.08.12.669959

humanproteomics

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Cancer BiologybioRxivPreprintApr 27, 2025

Tumor-specific draining lymph node CD8 T cells orchestrate an anti-tumor response to neoadjuvant PD-1 immune checkpoint blockade

Rachel Honigsberg, Tatiana Cruz, Liron Yoffe…·Jonathan Villena‐Vargas

This study identifies two transcriptionally distinct CD8 T cell populations in tumor-draining lymph nodes that are shaped by neoadjuvant chemoimmunotherapy and influence tumor and blood T cell environments.

3 citations

humanscRNA-seq

𝕏 PostBluesky