Author
Weill Cornell MedicineORCID 0009-0003-9569-5713Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Myung Soo Ko, Henry Withers, Divya Ramchandani…·Vivek Mittal
FASN-driven lipogenesis sustains EGFR palmitoylation and PI3K-AKT-mTOR signaling, suppressing tumor MHC-I antigen presentation; blocking it curbs TNBC metastasis in mice via CD8 T cell recognition.
Tatiana Cruz, Rachel Honigsberg, Geoffrey J. Markowitz…·Jonathan Villena‐Vargas
Neoadjuvant IL-15 with PD-1 blockade expands lymph node clonal diversity and preserves stem-like CD8 T cell features, yielding superior antitumor efficacy, durable memory, and reduced metastatic recurrence.
Rachel Honigsberg, Tatiana Cruz, Liron Yoffe…·Jonathan Villena‐Vargas
This study identifies two transcriptionally distinct CD8 T cell populations in tumor-draining lymph nodes that are shaped by neoadjuvant chemoimmunotherapy and influence tumor and blood T cell environments.
Junbum Kim, Hiranmayi Ravichandran, Liron Yoffe…·Olivier Elemento
This study profiles early-stage lung adenocarcinoma using multiplexed imaging mass cytometry to reveal two progression pathways: inflammation-driven and fibrosis-driven, with EMT masking malignant cell expansion.