Author

Tatiana Cruz

Weill Cornell MedicineORCID 0000-0002-9874-0802Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell type annotation· 2 Research Focus:clustering· 2 Research Focus:differential expression· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Arshdeep SinghiD· 2 shared Geoffrey J. MarkowitziD· 2 shared Jonathan Villena‐VargasiD· 2 shared Liron YoffeiD· 2 shared Marissa M. MichaeliD· 2 shared Meixian Stephanie Tang· 2 shared Nasser Khaled AltorkiiD· 2 shared Olivier ElementoiD· 2 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersImmunology

Arshdeep SinghORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Tumor-draining lymph node derived CD8 T cells sustain durable systemic immunity after neoadjuvant IL-15 and PD-1 blockade

Tatiana Cruz, Rachel Honigsberg, Geoffrey J. Markowitz, Dicle Özge Özgenel, Arshdeep Singh, Meixian Stephanie Tang, Stella A. Martomo, Liron Yoffe, Yongfeng He, Yang Bai, Jeegar P. Patel, Marissa M. Michael, Mitchell T. Martin, Timothy E. McGraw, Olivier Elemento, , Jonathan Villena‐Vargas

Neoadjuvant IL-15 with PD-1 blockade expands lymph node clonal diversity and preserves stem-like CD8 T cell features, yielding superior antitumor efficacy, durable memory, and reduced metastatic recurrence.

bioRxiv · Aug 12, 2025 · PreprintImmunology

Tumor-specific draining lymph node CD8 T cells orchestrate an anti-tumor response to neoadjuvant PD-1 immune checkpoint blockade

Rachel Honigsberg, Tatiana Cruz, Liron Yoffe, Meixian Stephanie Tang, Ozge Dicle, Geoffrey J. Markowitz, Marissa M. Michael, Arshdeep Singh, Nasser Khaled Altorki, Olivier Elemento, Jonathan Villena‐Vargas

This study identifies two transcriptionally distinct CD8 T cell populations in tumor-draining lymph nodes that are shaped by neoadjuvant chemoimmunotherapy and influence tumor and blood T cell environments.

bioRxiv · Apr 27, 2025 · PreprintCancer Biology