GeneticsThe Journal of Cell BiologyPeer-reviewed
Developmentally-orchestrated mitochondrial processes prime the selective inheritance against harmful mitochondrial DNA mutations
Zhe Chen, Zongheng Wang, Guofeng Zhang…·Hong Xu
The paper investigates mtDNA selective inheritance in Drosophila, showing that developmentally-orchestrated mitochondrial processes like fission and transcription enable purifying selection against harmful mutations.
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