Author

Karlie Edwards

University of British ColumbiaORCID 0000-0002-0333-2137Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 2

Signature Assays, Organisms & Methods

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Assay:DNA methylation· 2 Organism:human· 2 Research Focus:deconvolution· 1 Research Focus:gene regulatory network inference· 1 Approach:machine learning (classical)· 1 Approach:statistical model· 1

Frequent Co-Authors

Chaini KonwariD· 2 shared Elinor SimonsiD· 2 shared Erick I. Navarro‐DelgadoiD· 2 shared Maggie P. FuiD· 2 shared Michael Steffen KoboriD· 2 shared Padmaja SubbaraoiD· 2 shared Piush J. MandhaneiD· 2 shared Sarah M. MerrilliD· 2 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersBioinformatics

Chaini KonwarORCID

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2 papers

Recent·Most cited

RAMEN: Dissecting individual, additive and interactive gene-environment contributions to DNA methylome variability in cord blood

Erick I. Navarro‐Delgado, Darina Czamara, Karlie Edwards, Maggie P. Fu, Sarah M. Merrill, Chaini Konwar, Julie L. MacIsaac, David T S Lin, Piush J. Mandhane, Elinor Simons, Padmaja Subbarao, Theo J. Moraes, Jari M. T. Lahti, Gregory E. Miller, Elisabeth B. Binder, , Michael Steffen Kobor

RAMEN dissects gene-environment contributions to DNA methylome variability in cord blood, finding genetics explains the largest proportion of DNAme variance.

Genome biology · Dec 10, 2025Peer-reviewedBioinformatics

Advancing Pediatric and Longitudinal DNA Methylation Studies with CellsPickMe, an Integrated Blood Cell Deconvolution Method

Maggie P. Fu, Karlie Edwards, Erick I. Navarro‐Delgado, Sarah M. Merrill, Negusse Tadesse Kitaba, Chaini Konwar, Piush J. Mandhane, Elinor Simons, Padmaja Subbarao, Theo J. Moraes, John W. Holloway, Stuart E. Turvey, Michael Steffen Kobor

CellsPickMe improves blood cell deconvolution in longitudinal DNA methylation studies by integrating cord and adult references, enhancing accuracy across developmental stages.

bioRxiv · Apr 22, 2025 · PreprintBioinformatics