John W. Holloway

This study identifies immune-related gene expression differences in paediatric patients with SARS-CoV-2 compared to other lower respiratory tract infections.

The paper identifies non-canonical FBN1 splice variants in undiagnosed Marfan syndrome families using genome sequencing and RNA testing, finding 20 candidate variants with significant enrichment in FTAAD cases.

CellsPickMe improves blood cell deconvolution in longitudinal DNA methylation studies by integrating cord and adult references, enhancing accuracy across developmental stages.

This study identifies ANXA1 as a susceptibility locus for persistent wheezing through a meta-analysis of GWAS data from UK birth cohorts.

This study identifies DNA methylation changes in offspring linked to fathers' preconception smoking, with specific CpG sites associated with asthma, wheezing, and BMI.

The paper compares immune responses in influenza and SARS-CoV-2 infected patients and COVID-19 survivors using transcriptomic data, identifying distinct immune signatures and prognostic indicators.

This study identifies genetic effects on birth weight and their impact on cardio-metabolic traits, distinguishing fetal and maternal contributions.

This study identifies maternal genetic variants associated with offspring birth weight using GWAS and SEM, showing independent effects from fetal genetics.

This study investigates the genetic contributions to gestational weight gain, finding that maternal common variants explain about 20% of variability, while fetal variants have a minor role.

This study identifies genetic loci associated with early childhood growth phenotypes and links them to later adiposity traits, suggesting potential targets for obesity prevention.