Cereblon Promotes Influenza Virus Replication through AMPK Ubiquitination
Thu Ha Nguyen, Dong Ju Lee, Mahmoud Soliman, Muhammad Sharif, Myra D.T. Hosmillo, Hyung-Jun Kwon, Seong-Hun Jeong, Dae‐Eun Cheong, Hae-Rang Seo, Sunwoo Lee, Don‐Kyu Kim, Chul-Seung Park, Hueng-Sik Choi, Tae–Il Jeon, Ian Goodfellow, Kyoung‐Oh Cho
This paper identifies cereblon (CRBN) as a host factor that promotes influenza virus replication by degrading AMPK, shifting cellular metabolism to support viral growth.
Biochemistry and Biophysics Reports · Sep 28, 2026Peer-reviewedMicrobiology