Author

Andrew J. McDonald

Leiden University Medical CenterORCID 0000-0002-0349-8276Unclaimed ORCID profile · follow to get notified of new preprints

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Neuroscience· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Aat A. MulderiD· 1 shared Carmen GallegoiD· 1 shared Charlotte A. AndriesseniD· 1 shared Hailiang MeiiD· 1 shared Harald M. M. MikkersiD· 1 shared Ioannis MoustakasiD· 1 shared Jan WijnholdsiD· 1 shared Roman I. KoningiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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9 top collaborators · 36 mutual co-author links

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1 shared paperNeuroscience

Aat A. MulderORCID

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1 paper

Recent·Most cited

NeuroscienceStem CellsPeer-reviewedAug 10, 2026

Loss of ABCA4 from photoreceptor discs triggers changes in glial cell homeostasis

Rossella Valenzano, Andrew J. McDonald, Carmen Gallego…·Jan Wijnholds

This study uses hiPSC-derived retinal organoids to show that ABCA4 loss in photoreceptors disrupts glial cell homeostasis, suggesting a role for glial cells in Stargardt disease progression.

DOI 10.1093/stmcls/sxag045

humanbulk RNA-seq

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