Aat A. Mulder

This study demonstrates that high-capacity adenoviral vectors can restore USH2A protein expression and its interacting partners in USH2A-defective retinal organoids.

This study uses hiPSC-derived retinal organoids to show that ABCA4 loss in photoreceptors disrupts glial cell homeostasis, suggesting a role for glial cells in Stargardt disease progression.

This paper investigates how a COL6A3 mutation affects chondrocyte response to mechanical stress in a human iPSC-derived cartilage organoid model, finding reduced PCM protein binding and impaired stress response.