Author

Changjiu He

Huazhong Agricultural UniversityORCID 0000-0002-0350-9799Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 2 Physiology· 1

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:mouse· 3 Assay:spatial transcriptomics· 2 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Hongru ShiiD· 3 shared Jianning LiaoiD· 3 shared Wenkai Ke· 3 shared Yongheng Zhao· 3 shared Bowen Tan· 2 shared Guoshi LiuiD· 2 shared Hao Wu· 2 shared Xiaodong Wang· 2 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersCell Biology

Hongru ShiORCID

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3 papers

Recent·Most cited

Granulosa cell glycogen fuels the avascular corpus luteum

Jianning Liao, Qinghua Liu, Cong Liu, Guiqiong Liu, Xiang Olivia Li, X Wang, Yaqin Wang, Ruiyan Liu, Hao Wu, Chaoli Wang, Hongru Shi, Yongheng Zhao, Wenkai Ke, Zaohong Ran, Zian Wu, , Changjiu He

This study identifies GC energy storage as a mechanism enabling avascular corpus luteum function by glycogen catabolism, with implications for reproductive health.

Proceedings of the National Academy of Sciences · Jul 1, 2026Peer-reviewedPhysiology

FOSL2 regulates gonadotropin-dependent folliculogenesis through feedback amplification of FSH/FSHR signaling

Hongru Shi, Chaoli Chen, Zaohong Ran, Jianning Liao, Zian Wu, Xiaodong Wang, Yongheng Zhao, Wenkai Ke, Bowen Tan, Yun Liu, You‐Qiang Su, Wei Ren, Xiang Li, Changjiu He

This study identifies FOSL2 as a key regulator of FSH/FSHR signaling in folliculogenesis, showing it enhances FSHR transcription and forms a self-amplifying loop critical for reproductive function.

bioRxiv · Mar 11, 2025 · PreprintCell Biology

Granulosa cell-layer stiffening prevents the granulosa cells from escaping the post-ovulatory follicle

Xiaodong Wang, Jianning Liao, Hongru Shi, Yongheng Zhao, Wenkai Ke, Hao Wu, Guoshi Liu, Xiang Li, Changjiu He

The paper shows that granulosa cell-layer stiffening, driven by focal adhesion assembly and LH signaling, prevents granulosa cells from escaping the post-ovulatory follicle.

bioRxiv · Feb 6, 2024Cell Biology