You‐Qiang Su

This study identifies FOSL2 as a key regulator of FSH/FSHR signaling in folliculogenesis, showing it enhances FSHR transcription and forms a self-amplifying loop critical for reproductive function.

The paper constructs a longitudinal single-cell atlas of cynomolgus monkey ovaries across 22 years, identifies a novel oocyte type, and develops a transcriptomic ovarian clock applicable to humans.

This study shows that piRNAs are essential for generating functional oocytes in golden hamsters, with defects leading to sterility and embryonic arrest.