X Wang

The paper uses a protein language model to analyze the evolutionary history of bacterial aromatic polyketide ketosynthases and chain length factors, identifying a shared ancestral cluster and distinct evolutionary paths.

The paper shows that demographic compensation in alpine grassland species buffers population decline under heavy grazing, supporting the Intermediate Disturbance Hypothesis at the population level.

This study identifies AMPKγ2 deacetylation as a driver of Doxorubicin-induced cardiomyopathy through nucleolar stress and p53-mediated apoptosis, suggesting HDAC inhibitors could mitigate cardiac toxicity.

This study identifies GC energy storage as a mechanism enabling avascular corpus luteum function by glycogen catabolism, with implications for reproductive health.

The paper identifies a cis-regulatory variant in the ASIP gene associated with gray coat color in donkeys through genome-wide analysis and functional validation.

This study shows that NF1 deficiency in glioblastoma promotes metabolic reprogramming and epithelial-mesenchymal transition through AKT/mTOR activation and MFN1 regulation.

This study examines how environmental gradients influence phenotypic adaptation in Muscovy ducks across Benin's agroecological zones, providing evidence for climate-responsive livestock policy.

The paper introduces Seq2Kd, a deep learning model predicting TF-DNA binding affinity using high-throughput Kd measurements, and provides a web portal for functional genomics and disease research.

The paper introduces a genomic foundation model to detect transposable element impacts on rice genome architecture without alignment, revealing chromatin-domain-scale structural divergence.

The paper introduces mChIP-seq, a multiplex epigenomic profiling technology, and demonstrates its application in identifying cancer-specific histone features in both cellular and circulating nucleosomes.

The paper investigates the interactions between Dachs, Dlish, and App in Fat-Dachsous signaling, showing their roles in regulating each other and mediating signaling through palmitoylation and localization.