Author

Guoshi Liu

China Agricultural UniversityORCID 0000-0002-5688-3645Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Developmental Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Organism:mouse· 2 Assay:proteomics· 2 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1

Frequent Co-Authors

Changjiu HeiD· 2 shared Hao Wu· 2 shared Hongru ShiiD· 2 shared Jianning LiaoiD· 2 shared Wenkai Ke· 2 shared Yongheng Zhao· 2 shared Boda Chen· 1 shared Bowen Tan· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersPhysiology

Changjiu HeORCID

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3 papers

Recent·Most cited

Granulosa cell glycogen fuels the avascular corpus luteum

Jianning Liao, Qinghua Liu, Cong Liu, Guiqiong Liu, Xiang Olivia Li, X Wang, Yaqin Wang, Ruiyan Liu, Hao Wu, Chaoli Wang, Hongru Shi, Yongheng Zhao, Wenkai Ke, Zaohong Ran, Zian Wu, , Changjiu He

This study identifies GC energy storage as a mechanism enabling avascular corpus luteum function by glycogen catabolism, with implications for reproductive health.

Proceedings of the National Academy of Sciences · Jul 1, 2026Peer-reviewedPhysiology

GPLD1 Regulates the Shedding of IZUMO1R to Block Polyspermy in Porcine Oocyte

Boda Chen, Luting Shi, Fan Xia, Xingguo Chen, Jingyi Wang, Sitong Gao, Xiaoqian Zhou, Pengyun Ji, GuoShi Liu, Lu Zhang

The paper identifies GPLD1 as the enzyme mediating JUNO shedding in porcine oocytes, which is critical for preventing polyspermy and improving IVF outcomes.

bioRxiv · Apr 5, 2026 · PreprintDevelopmental Biology

Granulosa cell-layer stiffening prevents the granulosa cells from escaping the post-ovulatory follicle

Xiaodong Wang, Jianning Liao, Hongru Shi, Yongheng Zhao, Wenkai Ke, Hao Wu, Guoshi Liu, Xiang Li, Changjiu He

The paper shows that granulosa cell-layer stiffening, driven by focal adhesion assembly and LH signaling, prevents granulosa cells from escaping the post-ovulatory follicle.

bioRxiv · Feb 6, 2024Cell Biology