In vitro evidence for bisphenol A as a human liver carcinogen: Environmentally relevant doses inhibit cancer protective ESR1 signaling in a human liver cell line
Emma Weeks, Scott R. Kennedy, Robert P. Searles, Samantha Carrothers, Brett A. Davis, Lucia Carbone, Mitchell S. Turker, R. Stephen Lloyd, Caren Weinhouse
This study shows that bisphenol A inhibits cancer-protective ESR1 signaling in human liver cells at environmentally relevant doses, suggesting it promotes liver cancer.
bioRxiv · Dec 22, 2025 · PreprintPharmacology & Toxicology