Suzanne S. Fei

Sex-Dependent Epigenomic and Transcriptomic Reprogramming Links Maternal Obesity to Cardiac Remodeling in Adult Offspring

This study shows maternal obesity causes sex-dependent epigenetic and transcriptomic changes in offspring hearts, leading to sex-specific cardiac remodeling and disease risk.

Chronic Ethanol Drinking Alters Medial Prefrontal Cortex and Nucleus Accumbens Astrocyte Translatome and Extracellular Matrix Glycosaminoglycans

This study identifies sex- and region-specific astrocyte molecular changes in response to chronic ethanol, highlighting extracellular matrix and glycosaminoglycan remodeling as key factors in ethanol-related neuroplasticity.

Infection Of Rhesus Macaques With Onyong-nyong Virus UVIR-O804 Recapitulates Key Aspects of Human Clinical Disease

This study infects rhesus macaques with a recent ONNV clinical isolate, demonstrating viremia, immune activation, and clinical disease features similar to human infection.

Long Noncoding RNAs Preserve Pancreatic Cancer Identity and Resist Cell Fate Conversion

This study identifies long noncoding RNAs as key regulators of pancreatic cancer identity and resistance to reprogramming.

Metabolomic and transcriptomic remodeling of bone marrow myeloid cells in response to maternal obesity

This study shows that maternal obesity alters lipid metabolism, metabolomics, and gene expression in bone marrow myeloid cells of offspring, potentially contributing to adult metabolic and cardiovascular disease risk.

A Systematic Review and Meta-analysis on the Transcriptomic Signatures in Alcohol Use Disorder

This study performs a cross-species meta-analysis of transcriptomic data from AUD patients and animal models to identify common differentially expressed genes and pathways involved in AUD.

Transcriptional profiling of mucus production and modification in rhesus macaque endocervical cells under hormonal regulation

This study identifies hormone-regulated genes in endocervical mucus production using RNA-sequencing in rhesus macaques.

Molecular Contribution to Embryonic Aneuploidy and Genotypic Complexity During Initial Cleavage Divisions of Mammalian Development

The paper investigates molecular mechanisms of aneuploidy during early mammalian embryogenesis, revealing the role of mitotic checkpoint proteins and chromosomal mis-segregation in developmental arrest.

Single-Cell Sequencing of Primate Preimplantation Embryos Reveals Chromosome Elimination Via Cellular Fragmentation and Blastomere Exclusion

The paper uses single-cell DNA sequencing in non-human primates to show that chromosomal errors in embryos are encapsulated into micronuclei, fragmented, or excluded to prevent aneuploidy.