Author

Patrick A. Gladding

North Shore HospitalORCID 0000-0002-0380-3592Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:DNA methylation· 1 Approach:experimental assay· 1 Approach:statistical model· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Allison L. MilleriD· 1 shared John F. PearsoniD· 1 shared John Mackay· 1 shared Kate Kilpatrick· 1 shared Kevin Smith· 1 shared Luke BoyleiD· 1 shared Martin Alexander KennedyiD· 1 shared Nick James· 1 shared

Activity by Year

2018-2019 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperGenetics

Allison L. MillerORCID

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2 papers

Recent·Most cited

A Multiplex Pharmacogenetics Assay using the MinION Nanopore Sequencing Device

Yusmiati Liau, Simone L. Cree, Simran D. S. Maggo, Allison L. Miller, John F. Pearson, Patrick A. Gladding, Martin Alexander Kennedy

The paper develops a multiplex pharmacogenetics assay using MinION nanopore sequencing to genotype variants related to clopidogrel and warfarin, achieving >90% accuracy for most variants.

Pharmacogenetics and Genomics · Sep 20, 2019Peer-reviewedGenetics

A Propensity-Matched Nested Case-Control Study of Acute Coronary Syndrome Patients Genotyped for CYP2C19

Kate Kilpatrick, Nick James, Kevin Smith, John Mackay, Phillip Shepherd, Luke Boyle, Quentin Thurier, Zina Ayar, Patrick A. Gladding

This study evaluates the outcomes of acute coronary syndrome patients genotyped for CYP2C19, comparing personalized antiplatelet therapy with ticagrelor and clopidogrel.

Heart Lung and Circulation · Jan 1, 2018Peer-reviewedGenetic & Genomic Medicine