Simran D. S. Maggo

Identifying Opioid-Related Pharmacogenomic Variants in High-Risk Hospitalized Infants: A Pilot Study

This study identifies opioid-related pharmacogenomic variants in high-risk hospitalized infants, finding higher homozygosity for ABCB1 variants and lower for COMT and OPRM1 compared to a general population database.

Allelic diversity of the pharmacogene CYP2D6 in New Zealand Maori and Pacific peoples

The paper identifies novel CYP2D6 variants and suballeles in New Zealand Māori and Pacific populations, highlighting the high frequency of CYP2D6*71.

A Multiplex Pharmacogenetics Assay using the MinION Nanopore Sequencing Device

The paper develops a multiplex pharmacogenetics assay using MinION nanopore sequencing to genotype variants related to clopidogrel and warfarin, achieving >90% accuracy for most variants.

Nanopore sequencing of the pharmacogene CYP2D6 allows simultaneous haplotyping and detection of duplications

This study uses nanopore sequencing to genotype CYP2D6, accurately haplotype alleles, and detect duplications by analyzing allelic balance.