Helen N. Schwerdt

Striatal dopamine signals internal states related to behavioral performance over prolonged timescales in monkeys

This study shows that dopamine signals in the striatum track slow internal states of behavioral performance, distinct from reward prediction errors, and are organized by task demands.

Functional Dichotomy of Orbitofrontal Cortex and Anterior Cingulate Cortex Subregions in Decision-Making and Brain-Body Regulation

This study investigates the functional roles of the caudal orbitofrontal cortex (cOFC) and pregenual anterior cingulate cortex (pACC) in macaques using multimodal recordings and electrical microstimulation, finding distinct roles in decision-making and autonomic responses.

Micro-invasive probes for monitoring electrical and chemical neural activity in nonhuman primates

This paper develops micro-invasive probes for dual chemical and electrical neural activity recording in nonhuman primates, demonstrating long-term functionality over one year.

Aseptic, semi-sealed cranial chamber implants for chronic multi-channel neurochemical and electrophysiological neural recording in nonhuman primates

This paper describes a new neural implant that enables long-term, aseptic recording of both neurochemical and electrophysiological activity in nonhuman primates.

Synchronous Measurements of Extracellular Action Potentials and Neurochemical Activity with Carbon Fiber Electrodes in Nonhuman Primates

The paper develops a method to simultaneously measure dopamine and neuronal spikes in monkeys using carbon fiber electrodes and validates it for cell-type specific activity related to behavior.

An open-source MRI compatible frame for multimodal presurgical mapping in macaque and capuchin monkeys

The paper introduces an open-source, 3D-printable MRI-compatible stereotaxic frame for nonhuman primates, enabling accurate multimodal presurgical mapping and deep-brain interventions.