Author

Erin M. Coyne

Johns Hopkins UniversityORCID 0000-0002-0393-6600Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Alexei HernandeziD· 2 shared Jae Woo LeeiD· 2 shared Sarah M. ShiniD· 2 shared Won Jin HoiD· 2 shared Yeonju ChoiD· 2 shared Andrew J. EwaldiD· 1 shared Anneliese MarkusiD· 1 shared Antoine de Mathelin· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersCancer Biology

Alexei HernandezORCID

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3 papers

Recent·Most cited

Cancer BiologybioRxivPreprintFeb 17, 2026

A Pan-Cancer Ex Vivo Drug Screen Atlas for Functional Precision Oncology

Karl Pichotta, Jessica B. White, Jeffrey F. Quinn…·Wesley Tansey

The paper presents a pan-cancer ex vivo drug screen atlas with 2.1M experiments, identifying tissue-specific drug sensitivities and demonstrating their predictive value for clinical profiles.

DOI 10.64898/2026.02.14.705918

humanorganoid / primary culture

𝕏 PostBluesky

Cancer BiologybioRxivPreprintJan 7, 2025

Cancer associated fibroblasts drive epithelial to mesenchymal transition and classical to basal change in pancreatic ductal adenocarcinoma cells with loss of IL-8 expression

Samantha R. Guinn, Brayan Perez, Joseph A. Tandurella…·Jacquelyn W. Zimmerman

The paper investigates how cancer-associated fibroblasts (CAF) influence tumor cell behavior in pancreatic ductal adenocarcinoma by driving EMT and altering cell subtypes, with IL-8 playing a key modulatory role.

2 citations

humanbulk RNA-seq

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Cancer BiologyOncogenePeer-reviewedAug 20, 2024

Mapping the breast tumor microenvironment: proximity analysis reveals spatial relationships between macrophage subtypes and metastasis-initiating cancer cells

Eloïse M. Grasset, Atul M. Deshpande, Jae Woo Lee…·Won Jin Ho

The paper uses spatial analysis to show metastasis-initiating cancer cells in breast tumors are closely associated with specific macrophage subtypes, suggesting these interactions promote metastasis.

17 citations

humanimaging

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