Author

Jae Woo Lee

Johns Hopkins UniversityORCID 0000-0002-0735-5707Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Jae Woo Lee2 papers · University of California, Los Angeles

Biology Disciplines

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Cancer Biology· 3 Systems Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 2 Approach:experimental assay· 2 Assay:imaging· 2 Research Focus:spatial domain detection· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

Alexei HernandeziD· 3 shared Sarah M. ShiniD· 3 shared Won Jin HoiD· 3 shared Yeonju ChoiD· 3 shared Atul M. DeshpandeiD· 2 shared Elizabeth M. JaffeeiD· 2 shared Erin M. CoyneiD· 2 shared Laura DeLong WoodiD· 2 shared

Activity by Year

2024-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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3 shared papersCancer Biology

Alexei HernandezORCID

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Author profile →

4 papers

Recent·Most cited

Multi-omic profiling of intraductal papillary neoplasms of the pancreas reveals distinct expression patterns and potential markers of progression

Yuefan Wang, T. Mamie Lih, Jae Woo Lee, Takao Ohtsuka, Yuto Hozaka, Mari A. Mino-Kenudson, Nazmi Volkan Adsay, Claudio Luchini, Aldo Scarpa, Ajay V. Maker, Grace Kim, Jorge Paulino, Lijun Chen, Jongmin Jacob Woo, Liyuan Jiao, , Ralph H. Hruban

This study profiles proteins and glycoproteins in pancreatic neoplasms to identify expression patterns and potential progression markers.

Cancer Cell · Aug 28, 2025Peer-reviewedCancer Biology

Modeling cellular influence delineates functionally relevant cellular neighborhoods in primary and metastatic pancreatic ductal adenocarcinoma.

Yeonju Cho, Jae Woo Lee, Sarah M. Shin, Alexei Hernandez, Xuan Yuan, Jowaly Schneider, Jody E. Hooper, Laura DeLong Wood, Elizabeth M. Jaffee, Atul M. Deshpande, Won Jin Ho

The paper introduces FunCN, a method to analyze cellular neighborhoods in PDAC, revealing distinct immune interactions in primary and metastatic sites.

bioRxiv · Jun 12, 2025 · PreprintSystems Biology

Cancer associated fibroblasts drive epithelial to mesenchymal transition and classical to basal change in pancreatic ductal adenocarcinoma cells with loss of IL-8 expression

Samantha R. Guinn, Brayan Perez, Joseph A. Tandurella, Mili Ramani, Jae Woo Lee, Daniel J. Zabransky, Emma Kartalia, Jignasha G. Patel, Haley Zlomke, Norman G. Nicolson, Sarah M. Shin, Benjamin Barrett, Nicholas Sun, Alexei Hernandez, Erin M. Coyne, , Jacquelyn W. Zimmerman

The paper investigates how cancer-associated fibroblasts (CAF) influence tumor cell behavior in pancreatic ductal adenocarcinoma by driving EMT and altering cell subtypes, with IL-8 playing a key modulatory role.

bioRxiv · Jan 7, 2025 · PreprintCancer Biology

Mapping the breast tumor microenvironment: proximity analysis reveals spatial relationships between macrophage subtypes and metastasis-initiating cancer cells

Eloïse M. Grasset, Atul M. Deshpande, Jae Woo Lee, Yeonju Cho, Sarah M. Shin, Erin M. Coyne, Alexei Hernandez, Xuan Yuan, Zhehao Zhang, Ashley Cimino‐Mathews, Andrew J. Ewald, Won Jin Ho

The paper uses spatial analysis to show metastasis-initiating cancer cells in breast tumors are closely associated with specific macrophage subtypes, suggesting these interactions promote metastasis.

Oncogene · Aug 20, 2024Peer-reviewedCancer Biology