Victor Klein-Sousa

This study uses cryo-EM and tomography to reveal the structural changes in bacteriophage P2 during tail contraction and host infection, identifying new architectural features and mechanisms of genome translocation.

This study resolves the structure of bacteriophage T4 at different stages, revealing mechanisms of genome delivery and superinfection exclusion.

This study identifies structural modularity in Klebsiella pneumoniae phage RBPs, showing how modular exchange drives host-range diversification across multiple scales.

This study investigates the molecular mechanism of the Druantia anti-phage defense system, showing that DruH-E provides robust immunity and revealing its DNA unwinding and regulation by ATP.

The paper defines a global map of receptor-binding protein compatibility for designing phages targeting Klebsiella and Acinetobacter species.

This paper introduces RBPseg, a method to predict high-confidence tail fiber structures using segmentation and deep learning, and validates it with experimental data and structural classification.

This study reveals the structure and mechanism of the Zorya anti-phage defense system using cryo-EM and functional assays, showing how it detects phage invasion and activates defense.