Damien Piel

This study introduces HIDEN-SEQ, a transposon-insertion sequencing method for phages, to systematically map gene essentiality and uncover previously unknown viral anti-defense factors.

This study resolves the structure of bacteriophage T4 at different stages, revealing mechanisms of genome delivery and superinfection exclusion.

This study investigates the molecular mechanism of the Druantia anti-phage defense system, showing that DruH-E provides robust immunity and revealing its DNA unwinding and regulation by ATP.

The paper investigates viral-host lineage stability and mobile element diversity in a marine community, finding that ecological constraints promote long-term stability and diversity of phages and mobile genetic elements.

The paper completes the BASEL phage collection by overcoming host limitations to isolate new phages, revealing insights into viral host recognition and bacterial immunity.

This study examines broad-host-range Vibrio phages, identifying genetic features and ecological trade-offs that influence their host range and environmental distribution.