Eric Westman

Global brain maintenance predicts well-preserved cognitive function: A pooled analysis of three longitudinal population-based Swedish cohorts

This study shows that maintaining brain integrity through aging is linked to better cognitive function and slower decline, with lifestyle factors like lower cardiovascular risk and no diabetes playing a role.

Altered empathy processing in frontotemporal dementiaA task-based fMRI study

This study uses fMRI to examine empathy processing in bvFTD patients and controls, finding reduced BOLD signal in key regions and altered connectivity patterns.

Lifelong olfactory deprivation-dependent cortical reorganization restricted to orbitofrontal cortex

The paper replicates and extends findings showing that lifelong olfactory deprivation leads to orbitofrontal cortex morphological changes, but not in piriform cortex.

MRI-derived brain age as a biomarker of ageing in rats: validation using a healthy lifestyle intervention

The paper develops a rat brain age prediction algorithm using MRI and validates it through a healthy lifestyle intervention, showing reduced brain ageing with environmental enrichment and dietary restriction.

The genetic architecture of human brainstem structures and their involvement in common brain disorders

The paper identifies genetic loci associated with brainstem volumes and finds genetic overlaps with psychiatric and neurological disorders.

Normal Olfactory Functional Connectivity Despite Life-Long Absence of Olfactory Experiences

The paper compares functional connectivity in olfactory cortex between individuals with congenital anosmia and controls, finding no atypical connectivity despite lifelong olfactory sensory loss.

Fully Bayesian longitudinal unsupervised learning for the assessment and visualization of AD heterogeneity and progression

The paper develops a Bayesian longitudinal clustering framework to identify distinct AD brain atrophy patterns and their progression, revealing heterogeneity in disease progression.

Medial temporal atrophy in preclinical dementia: visual and automated assessment during six year follow-up

The paper assesses longitudinal medial temporal lobe atrophy in preclinical dementia using visual and automated methods over six years, finding that visual ratings correlate with subcortical volumes but have low inter-rater agreement.

The heterogeneous functional architecture of the posteromedial cortex is associated with selective functional connectivity differences in Alzheimer’s disease

This study identifies functional connectivity differences in the posteromedial cortex across Alzheimer’s disease stages using constrained ICA and ADNI data.

Structural changes in secondary, but not primary, sensory cortex in individuals with congenital olfactory sensory loss

The paper examines structural brain changes in individuals with congenital olfactory loss, finding atrophy in olfactory sulci and increased volume in medial orbital gyri, suggesting differential plasticity in secondary vs. primary olfactory cortex.

Genetics of brain age suggest an overlap with common brain disorders

The paper estimates brain age gaps using MRI and machine learning in individuals with and without brain disorders, finding heritability and genetic overlap with common disorders.

BRAPH: A Graph Theory Software for the Analysis of Brain Connectivity

BRAPH is a MATLAB-based software for analyzing brain connectivity using graph theory, enabling structural and functional network analysis in neurological studies.