Lizhen Wu

Activation of mGlu2 receptors reverses persistent post-methamphetamine deficit in object-in-place recognition memory.

This study shows that mGlu2 receptor activation can reverse memory deficits caused by chronic methamphetamine use in rats, suggesting it as a potential therapeutic target.

Transcription elongation factor ELOF1 is required for efficient somatic hypermutation and class switch recombination

This study identifies ELOF1 as a critical factor for somatic hypermutation and class switch recombination by facilitating RNAPII pausing and AID targeting.

Voluntary alcohol intake alters the motivation to seek intravenous oxycodone and neuronal activation during the reinstatement of oxycodone and sucrose seeking

This study shows that voluntary alcohol intake reduces oxycodone seeking in female rats and alters neural activation during cue-primed reinstatement of drug seeking.

Resilience to anxiety and anhedonia after predator scent stress is accompanied by increased nucleus accumbens mGlu5 in female rats

This study finds that female rats exposed to predator scent stress show distinct behavioral and genetic responses compared to males, with Susceptible females having higher BLA mGlu5 mRNA than Resilient or Control rats.

Increased mGlu5 mRNA expression in BLA glutamate neurons facilitates resilience to the long- term effects of a single predator scent stress exposure.

The paper identifies increased mGlu5 mRNA expression in BLA glutamate neurons as a factor contributing to resilience to predator scent stress in rats.

Using rat operant delayed match-to-sample task to identify neural substrates recruited with increased working memory load.

This study uses a rat operant delayed match-to-sample task to identify neural substrates involved in working memory under varying load conditions.

Ceftriaxone and mGlu2/3 interactions in the nucleus accumbens core affect the reinstatement of cocaine-seeking in male and female rats

This study shows ceftriaxone reduces cocaine-seeking by interacting with mGlu2/3 receptors in the nucleus accumbens core, as blocking these receptors prevents ceftriaxone's effect.