Author

Pierre Duplouye

Lyon 1 UniversitéORCID 0009-0009-4131-8166Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Organism:human· 2 Research Focus:spatial domain detection· 2 Approach:statistical model· 2 Approach:biophysical modeling· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:experimental assay· 1

Frequent Co-Authors

Christophe CauxiD· 3 shared Margaux HubertiD· 3 shared Bertrand DuboisiD· 2 shared Jenny Valladeau‐GuilemondiD· 2 shared Justine BerthetiD· 2 shared Marie‐Cécile MichalletiD· 2 shared Albert Ndour· 1 shared Alexia GazeuiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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3 shared papersCancer Biology

Christophe CauxORCID

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3 papers

Recent·Most cited

Cancer BiologybioRxivPreprintMay 7, 2026

Specific dendritic cells spatial organization is associated to ICB Response in Non Small Cell Lung Cancer (NSCLC)

Élisa Gobbini, Pierre Duplouye, Miguel Hurtado…·Jenny Valladeau‐Guilemond

The paper examines the spatial organization of dendritic cell subsets in NSCLC patients treated with anti-PD1 and finds that cDC1-driven patterns correlate with prolonged ICB response.

DOI 10.64898/2026.05.04.720587

humanbulk RNA-seq

𝕏 PostBluesky

ImmunologybioRxivPreprintJan 17, 2025

Early Neutrophil Sensing Shapes the Innate Response to Preneoplastic Mammary Cells

Antoine Debiesse, Manuela Pereira-Abrantes, Lyvia Moudombi…·Marie‐Cécile Michallet

This study identifies neutrophils as the earliest immune cells involved in surveilling preneoplastic breast cancer cells through UPR activation and immunogenic signaling.

2 citations

mousebulk RNA-seq

𝕏 PostBluesky

Cancer BiologybioRxivPreprintFeb 6, 2024

Spatial architecture of CD8+ T cells and DC subsets is critical for the response to immune checkpoint inhibitors in melanoma

Elisa Gobbini, Margaux Hubert, Anne-Claire Doffin…·Jenny Valladeau-Guilemond

This study examines the spatial organization of dendritic cell (DC) subsets and their interactions with CD8+ T cells in melanoma patients, finding that proximity between cDC1 and CD8+ T cells correlates with response to immune checkpoint inhibitors.

DOI 10.1101/2024.02.06.579128

humanspatial transcriptomics

𝕏 PostBluesky