Author

A.A. Bhattacharya

University of PennsylvaniaORCID 0000-0002-0460-7876Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Assay:fluorescence / live-cell microscopy· 1

Frequent Co-Authors

Barry S. CoopermaniD· 2 shared Yale E. GoldmaniD· 2 shared Clark FritschiD· 1 shared Hong LiiD· 1 shared Hong LiiD· 1 shared John D. LueckiD· 1 shared Martin Y. NgiD· 1 shared Philip NelsoniD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersBiophysics

Barry S. CoopermanORCID

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2 papers

Recent·Most cited

Single-Molecule Studies of Cognate and Near-Cognate Elongation in an in vitro Eukaryotic Translation System

Clark Fritsch, A.A. Bhattacharya, Martin Y. Ng, Hong Li, Philip Nelson, Barry S. Cooperman, Yale E. Goldman

This study uses single-molecule techniques to analyze tRNA selection during eukaryotic translation, revealing faster near-cognate sampling and a negative correlation between near-cognate concentration and tRNA accommodation efficiency.

Biophysical Journal · Oct 10, 2025Peer-reviewedBiophysics

Mechanism-based approach in designing patient-specific combination therapies for nonsense mutation diseases

Saleem Y. Bhat, A.A. Bhattacharya, Hong Li, Xiaonan Cui, John D. Lueck, Yale E. Goldman, Barry S. Cooperman

This paper investigates how PTC identity and sequence context affect readthrough efficiency and ataluren's effectiveness, providing insights into patient-specific therapy design.

Nucleic Acids Research · Mar 7, 2025Peer-reviewedBiochemistry