Author

Clark Fritsch

Johns Hopkins UniversityORCID 0000-0002-7507-8967Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Assay:fluorescence / live-cell microscopy· 1

Frequent Co-Authors

A.A. BhattacharyaiD· 1 shared Barry S. CoopermaniD· 1 shared Hong LiiD· 1 shared Martin Y. NgiD· 1 shared Philip NelsoniD· 1 shared Yale E. GoldmaniD· 1 shared

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2025-2025 · peak 1/yr

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6 top collaborators · 15 mutual co-author links

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1 shared paperBiophysics

A.A. BhattacharyaORCID

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1 paper

Recent·Most cited

BiophysicsBiophysical JournalPeer-reviewedOct 10, 2025

Single-Molecule Studies of Cognate and Near-Cognate Elongation in an in vitro Eukaryotic Translation System

Clark Fritsch, A.A. Bhattacharya, Martin Y. Ng…·Yale E. Goldman

This study uses single-molecule techniques to analyze tRNA selection during eukaryotic translation, revealing faster near-cognate sampling and a negative correlation between near-cognate concentration and tRNA accommodation efficiency.

5 citations

fluorescence / live-cell microscopyexperimental assay

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