Diana Gutiérrez

This study analyzes the structure-function relationships and evolutionary origins of cell wall-binding domains in staphylococcal phage endolysins, finding that CBD specificity is not strongly correlated with phylogeny or host specificity.

This paper identifies a new SH3b_T family of CBDs in staphylococcal phage endolysins and shows how sequence differences and EAD-CBD combinations influence binding specificity and activity.

This paper introduces a bioluminescence-based ex vivo burn wound model to assess antibacterial compounds in real-time, validated with an engineered lysin.